B lymphocytes (or B cells) descend from bone marrow (BM) hematopoietic stem cells (HSC) and mediate humoral immunity by secreting antibodies. Early studies based on a selected set of surface and ...
B cells are classified as B-1 or B-2 cells depending on their developmental origin 1. B-1 cells, which mediate innate-like immunity by secreting natural antibodies, develop primarily in the fetal ...
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