Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...

Basel, April 17, 2023 Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers have identified an active multi-layer circuit that forms in the cortex during ...

A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

A layer deep in the cerebral cortex, which is the innermost layer of the mammalian brain, has recently been found to play a role in the regulation of brain states associated with wakefulness and ...

Droplets containing human iPSC-derived neural progenitors were 3D-printed to form 2-layer cerebral cortical tissue, which was cultured before implantation into a mouse brain slice. DNPs: deep-layer ...

Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers headed by a team at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) have ...

This manuscript presents a valuable analysis of how locomotion modulates the activity of different subtypes of cortical neurons in the mouse primary visual cortex, showing that locomotion more ...

Brain organoids reveal that two genetic mutations in DEPDC5 drive epilepsy, disrupting early brain development, and causing ...