A distinctive pattern of brain activity associated with conditions including deep anesthesia, coma and congenital brain disorders appears to represent the brain's shift into a protective, low-activity ...

Early identification of infants with hypoxic-ischemic encephalopathy who have adverse outcomes despite neuroprotection with therapeutic hypothermia (TH) is urgently needed. Recent studies have found ...

After suffering a traumatic brain injury, patients are often placed in a coma to give the brain time to heal and allow dangerous swelling to dissipate. These comas, which are induced with anesthesia ...

ERGENT’s motivating hypothesis is that there are specific criteria that if broadly applied, would identify patients with a high likelihood of having epilepsy caused by changes in single genes. As an ...

Panel A shows the EEG patterns when the patient is awake, with eyes open (left) and the alpha rhythm (10 Hz) with eyes closed (right). Panel B shows the EEG patterns during the states of general ...

Some protocols suggest phenytoin concentrations of 30 µg/ml and phenobarbital at concentrations of 100–150 µg/ml. Others recommend iv. LEV at infusion rates of up to 6000 mg/day, valproate or even ...

CAMBRIDGE, MA -- When patients undergo general anesthesia, their brain activity often slows down as they sink into unconsciousness. Higher doses of anesthetic drugs can induce an even deeper state of ...

When under-anesthetized, patients may have awareness during the procedure, which can be traumatic; when they are over-anesthetized, they may have alternating periods of no brain activity as measured ...

Whether the treatment of rhythmic and periodic electroencephalographic (EEG) patterns in comatose survivors of cardiac arrest improves outcomes is uncertain. We conducted an open-label trial of ...