A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...
The catalytic hydrogenation of carboxylic acids—the reduction of R–COOH functionalities to alcohols or hydrocarbons under a hydrogen atmosphere—stands at the interface of sustainable chemistry and ...
Carboxylic acids are ubiquitous in bioactive organic molecules and readily available chemical building blocks. Carboxylic acids can be converted into carboxy radicals that can initiate versatile ...
A proline derivative reacts with an alkyl iodide to create a complex new molecule with a bond at a key stereocenter in red. A new cross-coupling reaction weds chiral carboxylic acids, such as proline ...
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