Universal solid tumor therapy with CD5-deleted, DSG2-directed CAR-T cells. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their action relies on a specialized exchange zone called the "immune synapse," ...

Cytotoxic T lymphocytes are the body's specialized "killers", precisely eliminating infected or cancerous cells. Their action ...

The body’s “killer” T cells don’t just attack—they strike with astonishing precision, forming a tiny, highly organized contact zone that lets them destroy dangerous cells without harming their ...

Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body? There are instances where killer T cells—which are meant to precisely remove virus-infected ...

"Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?" There are instances where killer T cells—which are meant to precisely remove virus-infected ...

Natural killer cells are supposed to be the immune system’s first responders against cancer. They don’t need to be trained on ...

Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based cancer therapy. Helper T cells act as the immune system’s coordinators, helping ...

Supercharged ‘natural killer’ cells could become a potent way to reset a disordered immune system — and thus quench some autoimmune disorders. Results from two small clinical trials suggest that ...

Researchers at UC San Francisco have uncovered a new clue to how Epstein-Barr virus (EBV) could contribute to multiple sclerosis (MS), a chronic autoimmune disease that affects nearly one million ...