Taking tiny, frequent amounts of the psychedelic drug lysergic acid diethylamide (LSD) might temporarily elevate mood for people diagnosed with major depressive disorder. In a small pilot study, ...

A new study from the University of Virginia reveals that a widely used class of weight-loss drugs does more than suppress appetite-it directly alters brain circuits that control motivation and reward.

University of Virginia researchers have shown that newer oral GLP-1 weight-loss drugs directly alter brain circuits tied to motivation and reward, not just appetite. These medications engage a pathway ...

Forget the old egg-in-a-frying pan bit - scientists finally know what your brain really looks like on drugs. A team of British-based researchers have conducted the first brain scans of people under ...

For decades, LSD has been associated with vivid hallucinations and counterculture movements. But now, researchers at the University of California, Davis, have discovered a way to tweak this powerful ...

In 1943, biochemist Albert Hoffman accidentally ingested a chemical that he had synthesized from a fungus and discovered that it created hallucinations. The mind-bending chemical was lysergic acid ...

A National Institutes of Health (NIH)-funded study has found that an emerging class of GLP-1 weight-loss drugs suppress ...

GLP-1 weight-loss drugs alter brain circuits in the amygdala and dopamine system to reduce the motivation to seek out high-calorie foods.