These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

Structure of a lymph node showing the typical division into different territories for immune cells: B cells are shown in red, T cells in blue, lymphatic vessels in yellow, and stromal cells in cyan.

Germinal centers are engines of rapid evolution. These tiny clusters in the lymph nodes refine antibodies through proliferation and mutation, generating high-affinity B cells capable of controlling ...

In aggressive lymphomas, inflammatory messengers reprogram the “conductors” of the immune system, causing lymph node structure to collapse. A team led by Simon Haas describes in “Nature Cancer” this ...

The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes. Although these procedures play a major role in cancer staging and ...

On the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the bottom are the ...

Cancer that starts in the lymph nodes is lymphoma. Cancer may also spread from other areas of the body to various lymph nodes, including the neck. Swollen lymph nodes are usually due to a cause other ...