Mast cells have crucial roles in allergic and other inflammatory diseases. Preclinical approaches provide circumstantial evidence for mast cell involvement in many diseases, but these studies have ...

Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an allergen, ...

Mast cells are a crucial part of our immune defenses against bacteria, some parasites and venoms, but they are also key players in allergic reactions, in which inflammatory mediators, such as ...