Scientists have uncovered the intricate circuit cues behind neuronal cell maturation and migration, which is required for proper cognitive function. The journey of a thousand miles begins with a ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

Scientists have identified a protective brain pathway that may help slow the progression of Parkinson's disease by ...

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can cause significant nerve degeneration that results in the loss of memory, ...

The thermosensory neuron AFD unexpectedly modulates locomotion based on tactile experience through molecular and circuit mechanisms distinct from those underlying thermosensation.

Ordinary human cells, not just neurons, respond more strongly to memory signals when they arrive in spaced bursts rather than ...

Some people carry the full molecular burden of Alzheimer’s disease, brains loaded with amyloid plaques and tangled tau ...

New research has shown that Sonic Hedgehog (SHH)–Gli1 signaling in microglia amplifies inflammatory responses through the IKKβ/NF-κB pathway, contributing to dopaminergic neuron loss in Parkinson’s ...