The Journal of Immunology reports that vaccination of neonatal mice with group A Streptococcus promoted a clonal expansion of innate-like B cells that produce antibody against N-acetyl-D-glucosamine, ...

Type 1 diabetes arises through autoimmune destruction of insulin‐producing pancreatic β‐cells. MicroRNAs (miRNAs) have emerged as critical regulators at the interface of immune activation and β‐cell ...

Type 1 diabetes (T1D) is commonly diagnosed in childhood and the teen years. It’s a lifelong condition that requires treatment. Type 1 diabetes (T1D) is an autoimmune disease that occurs when the ...

While it has long been known that type 1 diabetes runs in families, experts are less certain about what actually starts the autoimmune attack that defines the disease. Most people with type 1 diabetes ...

SARS-CoV-2 infection is associated with a transient, nonsustained increase in new-onset type 1 diabetes risk among children and adults.

Researchers have discovered the novel mechanism that underlies a previously reported observation that infection by group A Streptococcus bacteria reduces the risk of later developing type 1 diabetes.

Vaccination of neonatal mice with group A Streptococcus promotes clonal expansion of B cells that produce antibody against GlcNAc. The association of reduced Type 1 diabetes risk after group A ...