"Despite significant advances in computational protein design in recent years, designing protein binders from scratch remains challenging," explains the study's first author, Kateryna Maksymenko. "To ...

Physical interactions between proteins influence anything from cell signaling and growth to immune responses, so the ability to control these interactions is of great interest to biologists.

For the field of drug development, hitting the right target with atomic precision to achieve therapeutic effect remains the core challenge. While traditional R&D pipelines are dependent on ...

BOSTON--(BUSINESS WIRE)--Manifold Bio, a platform therapeutics company pioneering direct-to-vivo drug discovery, today announced a joint study with NVIDIA to validate Proteina-Complexa, NVIDIA's ...

WATERTOWN, Mass.--(BUSINESS WIRE)--Dyno Therapeutics, Inc., a genetic technologies company applying AI to empower patients everywhere with genetic agency, today announced the launch of Dyno Psi-Phi ...

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...

Proteins are biology’s molecular machines. They’re our bodies’ construction workers—making muscle, bone, and brain; regulators—keeping systems in check; and local internet—responsible for the ...

The global structural properties of a protein, such as shape, fold and topology, strongly affect its function. Although recent breakthroughs in diffusion-based generative models have greatly advanced ...

In the human body, the boundary between health and severe illness can be microscopic. For decades, molecular scientists have grappled with a frustrating biological reality: The proteins driving ...

Since its release in 2024, the open-source platform BindCraft, developed at EPFL, has already disrupted the world of protein design. Physical interactions between proteins influence anything from cell ...

Dyno’s Psi-Phi generative protein design and agentic interfaces provide versatile AI models and agents that connect physical outcomes with computational workflows Dyno Therapeutics, Inc., a genetic ...