Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

RNA is the means of translating the genetic code embedded in DNA into proteins, which serve as enzymes, transporters, ...

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the ...

Panelists discuss how splice modifiers work by enhancing protein production from the SMN2 gene, with risdiplam (Evrysdi) being an oral daily medication and nusinersen (Spinraza) being administered ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

New findings challenge previous assumptions about nitric oxide in Alzheimer’s disease, and point to potential new therapeutic ...

A new AI-driven framework enables highly accurate prediction of RNA splicing and isoform usage for therapeutic applications.

Vigeneron GmbH has received IND approval from the FDA for VG-801, a novel mRNA trans-splicing gene therapy to treat Stargardt disease and other retinal dystrophies associated with mutations in the ...