Standardization is needed in CAR-T cell therapy development due to its inherent complexity. Chimeric antigen receptor (CAR)-T cells have already changed how certain cancers are treated. As of February ...

Using more exacting analytical tools can give a clearer assessment of gene-editing outcomes. Although many have never heard of it, β-thalassemia is one of the most common autosomal recessive diseases ...

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A recent review took a look at the promise of measuring circulating tumor DNA (ctDNA) with digital-droplet PCR (ddPCR) in pancreatic ductal adenocarcinoma (PDAC) as the landscape of this cancer ...

Droplet digital polymerase chain reaction (ddPCR) technology is emerging as an efficient, accurate, and precise way to measure transgene copy numbers. With it, scientists may screen for clonal ...

Bio-Rad (CA, USA), a clinical diagnostics products company, has launched a new ddPCR kit designed to assess AAV vector quality for gene therapy development. Vericheck ddPCR Empty-Full Capsid Kit can ...

A recently published paper in the Journal of Virological Methods is the first to directly compare ddPCR technology to RT-qPCR with multiplexed assays using the same reaction mix and cycling protocol ...

The study, using a BCR/ABL1 assay, found that the novel method is able to detect minimal residual disease (MRD) in a larger range of patients compared with quantitative real‐time polymerase chain ...

Droplet Digital TM PCR (ddPCR TM) has been an evolving tool for precision and absolute detection in genomics for over a decade. Now, new technological innovations have created a suite of options that ...

Bio-Rad Laboratories Inc. (NYSE: BIO and BIOb) today released the One-Step RT-ddPCR Advanced Kit for Probes which combines reverse transcription and Droplet Digital PCR (RT-ddPCR) for absolute RNA ...